Most Commonly Associated Disease
Myopathy

Category
Muscle enzymes

When to Order
* Concern for myositis
* Takes a bit longer than CPK to result

What It Means If Positive
* Values that are just above the upper limit of normal can happen without any particular disease associations.
* Moderately-highly elevated values raise concern for significant muscle breakdown.

What It Means If Negative
* Normal doesn’t rule out myositis

Of Note
* Aldolase is found in other tissues and not specific to muscle