Main Disease Association
Necrotizing myositis

Category
Antibody

When to Order
* Clinical signs and symptoms of inflammatory myopathy and necrosis seen on biopsy

What It Means If Positive
* Associated with necrotizing myositis (necrosis on biopsy)

What It Means If Negative
* Doesn’t help rule out myositis

Of Note
* May not be as responsive to systemic steroids as non-necrotizing myositis