Main Disease Associations
* Anti-synthetase syndrome
* Myositis
Category
Antibody
When to Order
* For patient with clinical signs and symptoms of anti-synthetase syndrome (clinical features: myositis, inflammatory arthritis, interstitial lung disease, Raynaud’s, rashes, mechanic’s hands)
What It Means If Positive
* Monitor for development of or progression of myositis, inflammatory arthritis, interstitial lung disease, Raynaud’s, rashes, mechanic’s hands
What It Means If Negative
* Doesn’t rule out anti-synthetase syndrome
From the American College of Rheumatology
