Main Disease Association
Sjogren’s disease
Category
Antibody
When to Order
* Dry eyes/mouth/other mucosal surfaces
* Part of SLE workup
What It Means If Positive
* Part of diagnostic criteria for Sjogren’s disease
* Also seen in SLE; increased risk for neonatal lupus in offspring
What It Means If Negative
* Doesn’t rule out Sjogren’s