Main Disease Associations
* Anti-synthetase syndrome
* Myositis

Category
Antibody

When to Order
* For patient with clinical signs and symptoms of anti-synthetase syndrome
* Clinical features: Myositis, inflammatory arthritis, interstitial lung disease, Raynaud’s, rashes, mechanic’s hands

What It Means If Positive
* Monitor for development of or progression of myositis, inflammatory arthritis, interstitial lung disease, Raynaud’s, rashes, mechanic’s hands

What It Means If Negative
* Doesn’t rule out antisynthetase syndrome